InvestigatorsInstitutions
Academic clinical research

Your synopsis, ready to submit before the end of the week.

Protocolis is the scientific, methodological and regulatory assistant for medical research investigators. The AI asks the right questions, structures your project's synopsis and protocol according to its regulatory framework, and delivers a Word or PDF document, in French and English, that meets institutional expectations. Hosted in France, your content stays confidential.

Try 7 days free Institutions
No credit cardCancel in 1 clickIsolated per user
protocolis.fr · studies · REHAB-COLO-2026
Illustrative preview
A prospective single-center trial on rehabilitation after colorectal surgery. For the primary endpoint, which primary indicator are you considering?
Length of stayClavien-Dindo complications ≥ IIReturn of bowel function
GDPR compliant
Hosted in France
Per-user data isolation

Method

Three steps. No blank page.

The investigator stays in control of every decision.

From idea to structured protocol, in a few hours. You collaborate with your AI ally: it asks the right questions, reviews the literature, and drafts your documents.

Pricing
01
Describe your project
A few sentences: your research question, your study population, your endpoint. No form to fill in blindly.
02
Build through conversation
The assistant follows up section by section, proposes methodological wording, searches PubMed and ClinicalTrials, computes the required sample size.
03
Export or share
Download the Word or PDF document, in French or English, compliant with regulatory standards, or send it directly to your methodologist or head of department via a secure link.

The regulatory framework

You describe your research. Protocolis infers the regulatory framework.

As you describe your project (population, data collected, patient pathway), the assistant identifies the applicable research category and the authorization circuit to follow.

RIPH 1
Interventional research
RIPH 2
Minimal risks & constraints
RIPH 3
Non-interventional
RNIPH
Research not involving the human person
Drug studies
Research on medicinal products
MD / IVD-MD
Medical devices & IVDs

What Protocolis brings you

A methodologist who never sleeps. Not a chatbot.

The assistant probes the grey areas.

Rather than a blank page, Protocolis asks the questions a methodologist would ask, in order, with examples tailored to your specialty.

  • Automatic detection of missing sections
  • Suggestions contextualized by specialty
  • Sample size and proposed statistical hypotheses
  • Timestamped conversation history, exportable
You described an open-label design. For a comparative trial, a control arm is expected. Do you prefer individual or cluster randomization?
Individual randomization, 1:1.
Perfect. With a binary primary endpoint and an assumed effect of 15%, I propose n = 212 (two-sided α = 0.05, power 0.80). Shall we validate?
Illustrative preview. Protocolis outputs constitute a methodological working basis: final validation remains the responsibility of the reference methodologist.

Frequently asked questions

Everything investigators ask us.

Protocolis processes no patient data. The tool produces methodological content (synopsis, protocol, bibliography) from your description of the project, not from individual data. Furthermore, your content (conversations, synopsis, imported documents) is never used to retrain the models. Contractual guarantee, isolation per institution workspace, hosting in France.

Protocolis does not replace your methodologist: it saves you the hours of upstream structuring, so the methodological review focuses on substance. The CRAs at pilot centers use it as a reference draft.

Protocolis proposes the sample size, the hypothesis, the test and the justification, based on the cited literature. For complex designs (cluster, adaptive sequential, Bayesian), it asks the right questions and structures your later exchange with your biostatistician.

Each study is isolated to your account (or to your institution's workspace on an institutional license). No leakage between institutions, no external access, including for our team, except with explicit consent for support.

You resume the conversation with the assistant by submitting the research-office feedback: it generates a revised version point by point. All iterations are kept and exportable.

Word (.docx) or PDF, in French or English, with a layout compliant with research-office standards. The PHRC-N letter of intent and the ethics-committee form are being added.

Another question? Write to us (answer within 24 business hours).

Ready to start

Your next synopsis, this afternoon.

7 days free, no credit card. Invite your team or your research office when you are ready.

Try for free Talk to the Protocolis team

No credit card · Cancel in 1 click · Hosted in France